Source identities checked 11 October 2026. Complete references remain available without search or scripts. Summaries distinguish observations, mechanisms and reviews.
Helfrich-Förster, C., Monecke, S., Spiousas, I., Hovestadt, T., Mitesser, O., & Wehr, T. A. (2021). Women temporarily synchronize their menstrual cycles with the luminance and gravimetric cycles of the Moon. Science Advances, 7(5), eabe1358. https://doi.org/10.1126/sciadv.abe1358
Selected long-term records from 22 women showed intermittent timing associations. The analysis does not establish universal synchronization, a gravity receptor, clinical benefit or an individual prediction.
Open source: Women temporarily synchronize their menstrual cycles with the luminance and gravimetric cycles of the MoonHelfrich-Förster, C., Domenie, E. D., Mitesser, O., Hovestadt, T., Ferlin, A., Wehr, T. A., Costa, R., & Montagnese, S. (2025). Synchronization of women’s menstruation with the Moon has decreased but remains detectable when gravitational pull is strong. Science Advances, 11(39), eadw4096. https://doi.org/10.1126/sciadv.adw4096
The authors compare selected long-term menstrual records across historical periods. They propose light exposure and gravitational timing as explanations for changed associations; this observational comparison does not isolate those causes or validate a cycle prediction.
Open source: Synchronization of women’s menstruation with the Moon has decreased but remains detectable when gravitational pull is strongEcochard, R., Stanford, J. B., Fehring, R. J., Schneider, M., Najmabadi, S., & Gronfier, C. (2024). Evidence that the woman’s ovarian cycle is driven by an internal circamonthly timing system. Science Advances, 10(15), eadg9646. https://doi.org/10.1126/sciadv.adg9646
Ecochard and colleagues analyze 26,912 cycles from 2,303 European women and 4,786 cycles from 721 North American women. Time-series characteristics support an internal timing hypothesis. The reported lunar alignment differs between populations; these records do not demonstrate a molecular lunar sensor or an effective fertility intervention.
Open source: Evidence that the woman’s ovarian cycle is driven by an internal circamonthly timing systemPoehn, B., Krishnan, S., Zurl, M., Coric, A., Rokvic, D., Häfker, N. S., Jaenicke, E., Arboleda, E., Orel, L., Raible, F., Wolf, E., & Tessmar-Raible, K. (2022). A Cryptochrome adopts distinct moon- and sunlight states and functions as sun- versus moonlight interpreter in monthly oscillator entrainment. Nature Communications, 13(1), 5220. https://doi.org/10.1038/s41467-022-32562-z
Experiments on Platynereis dumerilii and its L-Cryptochrome examine species-specific light responses relevant to reproductive timing. The marine bristle-worm findings do not establish a corresponding sensor in humans.
Open source: A Cryptochrome adopts distinct moon- and sunlight states and functions as sun- versus moonlight interpreter in monthly oscillator entrainmentRitter, A., & Tessmar-Raible, K. (2024). Time me by the moon. EMBO Reports, 25(8), 3169–3176. https://doi.org/10.1038/s44319-024-00196-5
Ritter and Tessmar-Raible review the evolution and function of lunar timing systems across organisms. This is a synthesis, not a new human experiment or proof that the same mechanism operates across species.
Open source: Time me by the moonWehr, T. A. (2018). Bipolar mood cycles and lunar tidal cycles. Molecular Psychiatry, 23(4), 923–931. https://doi.org/10.1038/mp.2016.263
A retrospective series of 17 selected patients explores mood-cycle timing and lunar tidal periods. The observations generate hypotheses; they do not establish gravitational causation, a population-wide mental-health effect or a treatment recommendation.
Open source: Bipolar mood cycles and lunar tidal cyclesAlberghina, D. (2025). A rhythmic dance: how lunar cycles influence reproductive behavior in vertebrates. Frontiers in Mammal Science, 4, 1690167. https://doi.org/10.3389/fmamm.2025.1690167
Alberghina’s mini review surveys vertebrate reproductive timing literature. Comparative observations depend on species and setting. The review supplies context for hypotheses; it does not independently demonstrate a human reproductive mechanism.
Open source: A rhythmic dance: how lunar cycles influence reproductive behavior in vertebratesDopico, X. C., Evangelou, M., Ferreira, R. C., Guo, H., Pekalski, M. L., Smyth, D. J., Cooper, N., Burren, O. S., Fulford, A. J., Hennig, B. J., Prentice, A. M., Ziegler, A. G., Bonifacio, E., Wallace, C., & Todd, J. A. (2015). Widespread seasonal gene expression reveals annual differences in human immunity and physiology. Nature Communications, 6(1), 7000. https://doi.org/10.1038/ncomms8000
Dopico and colleagues report seasonal expression in 5,136 of 22,822 genes tested in the BABYDIET blood-cell dataset, with comparisons across other cohorts and tissues. The proportion refers to that analysis, not every gene in every person. Seasonal immune patterns do not validate lunar, zodiac or individual energy predictions.
Open source: Widespread seasonal gene expression reveals annual differences in human immunity and physiologyMeyer, C., Muto, V., Jaspar, M., Kussé, C., Lambot, E., Chellappa, S. L., Degueldre, C., Balteau, E., Luxen, A., Middleton, B., Archer, S. N., Collette, F., Dijk, D. J., Phillips, C., Maquet, P., & Vandewalle, G. (2016). Seasonality in human cognitive brain responses. Proceedings of the National Academy of Sciences, 113(11), 3066–3071. https://doi.org/10.1073/pnas.1518129113
Meyer and colleagues examine task-related fMRI responses at different times of year after a controlled laboratory protocol. Seasonal brain-response differences do not mean that each person’s attention or memory performance peaks at a solstice or equinox. This study does not establish a lunar effect.
Open source: Seasonality in human cognitive brain responsesHohm, I., Wormley, A. S., Schaller, M., & Varnum, M. E. W. (2024). Homo temporus : Seasonal Cycles as a Fundamental Source of Variation in Human Psychology. Perspectives on Psychological Science, 19(1), 151–172. https://doi.org/10.1177/17456916231178695
Hohm and colleagues review seasonal variation and propose meteorological, ecological and sociocultural pathways for further study. This synthesis does not validate astrology, a universal seasonal energy schedule or an individual forecast.
Open source: Homo temporus : Seasonal Cycles as a Fundamental Source of Variation in Human Psychology